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Chemistry’s Second Fund: $500 Million in

Money talks. It always does. And right now Chemistry Ventures is speaking volumes.

The VC firm—born two years ago from the ashes of Bessemer Index Ventures and Andreessen Horowitz alumni—is pulling in $500 million. At least that’s what an SEC filing suggests for its second fund.

Ambitious. Almost audaciously so.

Launched with just $350 million back in day one, the firm has doubled its ambition. Founded by Mark Goldberg Ethan Kurzweil and Kristina Shen. They left their cushy spots at the big names—Index Bessemer and a16z—to strike out on their own. Smart move. Or so they hope.

They focus on early-stage startups. Specifically AI. Both the infrastructure holding it up and the apps riding on top. Their portfolio? Granola. Decagon. Persona. Serval. Nova Intelligence. You start seeing a pattern.

Goldberg came from Index. Kurzweil from Bessemer. Shen from a16z.

The plan was simple: combine that high-level experience with a fresh perspective. Skip the corporate bloat.

The Wall Street Journal says the second fund is already oversold. Everyone wants a piece of the action. It should close soon.

Did they hear back? No. Chemistry did not return requests for comment immediately. Silence is its own message.

This story was updated to clarify that Chemistry isn’t just betting on any tech. They’re betting on companies actually building within AI. Precision matters.

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